Publication: A novel hydrogen peroxide evolved CHO host can improve the expression of difficult to express bispecific antibodies
Publication featuring ChemStress®. The manufacture of bispecific antibodies by Chinese hamster ovary (CHO) cells is often hindered by lower product yields compared to monoclonal antibodies. Publication outlines the generation of a novel hydrogen peroxide evolved host using directed host cell evolution.
Mistry et al., Biotechnology and Bioengineering, 118, (2021) 2326–2337.