Products – ChemStress® Clone Robustness

Clone robustness ranking early in the process: ChemStress® simulates bioreactor stressful environments in a small scale culture.

Data-driven ranking analytics:
Test Clone robustness in response to small molecule stressors


Maximize performance in biomanufacturing based on deep cell function analytics

  • Select clones that are internally more robust
  • Rank your clones based on robustness
  • Enhance stability by identifying clones that are internally more stable
  • De-risks your process by selecting the most robust clones

ChemStress® Clone Robustness Applications

ChemStress® Clone Robustness Study


  • Selection of the best clone candidates is a significant and critical step to ensuring optimal performance in biomanufacturing 
  • Standard cell viability and titer measurements are not fully reflective of real bioprocessing environments



ChemStress®  empowers the selection of only the most robust clones by analyzing cell functional responses to a panel of 21 small chemical molecules, challenging key production pathways, and mimicking recurrent bioprocess stresses cells are likely to experience in production.

By applying the ChemStress® Robustness technology, it is possible to drive clone selection with rich functional performance information and advanced data analysis. The ChemStress® robustness ranking offers an innovative and actionable index to streamline your clone selection and maximize the production value of your process.

Want to discuss ChemStress® Clone & Media technology?

Dr. Alessandra Prinelli
Hi, I’m Alessandra, Technical Product Manager at ValitaCell. Fill in the form and I’ll get in touch with you to discuss how ChemStress® can transform your workflows.