Resources

Resource Categories: Publications Resources
Scientist using a Molecular Devices plate reader

Application Note: Valita®Titer and Molecular Devices

Discover how Valita®Titer can be combined with Molecular Device’s microplate reader to provide a high-throughput IgG quantitation platform for clone screening during drug discovery and development.

Application Note: Valita®Titer with Synthace.

Discover how your lab can reduce total hands on time by 55% by combining  Valita®Titer with Synthace software for automated, high-throughput IgG quantification.

Cell culture patent

ChemStress® Chemicals Specification

Discover ChemStress® chemicals concentrations, plate map and literature.

Active cell nucleus splitting

Publication: Cell function profiling to assess clone stability

Publication featuring ChemStress®. In cell line development the identification of stable CHO cells for production is a critical but onerous task. This publication outlines the use of ChemStress® cell function profiling that uses a panel of active chemicals to mimic known bioprocess stresses and challenge key pathways.

Dobson et al., Biotechnology and Bioengineering. 2020; 1–5

Biological cells

Publication: A platform for context-specific genetic engineering of recombinant protein production by CHO cells

Publication describes and validates the development of a high-throughput microscale platform featuring Valita®Titer technology.  The platform was used to compare and identify optimal cell engineering solutions for both transient and stable production of a model DTE IgG1 monoclonal antibody.

Cartwright et al., Journal of Biotechnology 312 (2020) 11–22

Application Note: Valita®Titer with Andrew Alliance

Learn how the high-throughput, IgG assay Valita®Titer, operates seamlessly with Andrew Alliance automation software to reduce human error and increase the production of reproducible, reliable data.

Opentrons O2 Automation technology

Application Note: Valita®Titer with Opentrons

This application note demonstrates how Valita®Titer, combined with Opentrons OT-2 automation technology and software can deliver a cost-effective and reproducible solution for accurate IgG quantification throughout drug manufacturing.

Download
Antibody

Publication: High-throughput quantitation of Fc-containing recombinant proteins in cell culture supernatant by fluorescence polarization spectroscop

Publication featuring Valita®Titer. Measurement of recombinant protein product titer critically underpins all biopharmaceutical manufacturing process development. This publication describes the use of Valita®Titer, a rapid 96-well assay, that enables high-throughput quantitation of recombinant immunoglobulin G and Fc-containing IgG derivatives in mammalian cell culture supernatant. 

Thompson et al., Analytical Biochemistry, 534 (2017) 49-55